How to Get Rid of Smile Lines? Smile Lines Treatment Options by Depth of the Fold
How to get rid of smile lines depends on whether your folds are superficial skin creases, fat pad descent, or bone absorption around the mouth. Fine surface lines improve with daily broad-spectrum sunscreen, topical retinoids, and hydration. Deeper grooves require clinical care, ranging from $77 to $537 (2 to 14 million VND) for hyaluronic acid dermal fillers to $575 to $1,074 (15 to 28 million VND) for thread lifts or $1,342 to $3,067 (35 to 80 million VND) for facelift surgery in Ho Chi Minh City.
Below is an overview of fold types, causes, topical home routines, clinical procedures with 2026 Ho Chi Minh City cost.

Key Takeaways
- Anatomic Distinction: Perioral folds include nasolabial folds (nostril to mouth corner), marionette lines (mouth corner to chin), and vertical lip lines (perioral smoker lines).
- Topical Boundaries: Prescription retinoids and daily SPF reduce fine surface creases by boosting collagen over months, but cannot lift descending cheek fat pads or structural hollows.
- Clinical Matching: Mild-to-moderate static folds respond well to hyaluronic acid fillers or biostimulators, while severe sagging requires thread suspension or surgical lifting.
- Layer Integration: Combining volumetric fillers with collagen-stimulating lasers or energy devices yields more natural, balanced results than over-filling a single groove.
What Are Smile Lines?
Smile lines refer to the dynamic and static folds that form around the lower face during expression and rest. These wrinkles fall into three anatomical categories:
- Nasolabial Folds: Grooves running from the outer edge of the nostrils down to the corners of the mouth.
- Marionette Lines: Vertical creases extending from the corners of the mouth down toward the chin, giving a downturned expression.
- Perioral Vertical Lines: Fine vertical creases along the upper and lower lip margins, often accentuated by repetitive lip puckering or smoking.
Dynamic lines appear only during facial expressions like laughing or smiling. Over time, collagen loss turns dynamic movements into static lines that remain visible even when facial muscles relax.
What Causes Smile Lines to Deepen?
Multiple structural factors contribute to deepening folds around the mouth:
- Collagen and Elastin Depletion: Natural aging reduces dermal structural proteins, thinning the skin layer around the lips.
- Cheek Fat Pad Descent: Midface fat pads shift downward due to gravity, hanging over the nasolabial boundary.
- Maxillary Bone Absorption: Gradual bone loss around the upper jaw reduces structural support beneath the soft tissues.
- UV Exposure: Sun damage breaks down elastic fibers and accelerates skin creasing.
- Repetitive Expressions and Habits: Frequent smoking or repetitive muscle movements deepen skin creases over time.

Self-Evaluating Your Fold Severity
Matching your fold depth to the correct treatment prevents unnecessary procedures or under-treating severe laxity:
| Severity Level | Visual Appearance | Anatomic Change | Matching Solution |
| Mild | Lines visible only during smiling or movement | Early surface collagen loss | Retinoids, sunscreen, HA mesotherapy |
| Moderate | Shallow static lines visible at rest | Mild cheek fat descent, shallow groove | Hyaluronic acid fillers, skin boosters |
| Severe | Deep static folds with skin overhang | Marked fat pad descent & bone loss | Collagen biostimulators, thread lifts |
| Advanced | Heavy jowls & loose skin extending to chin | Significant muscle & skin laxity | SMAS or deep plane facelift surgery |
How to Soften Smile Lines at Home
Topical skin care builds dermal thickness and slows wrinkle progression:
- Prescription Retinoids: Topical tretinoin or adapalene stimulates natural collagen synthesis over 3 to 6 months. Apply a pea-sized amount at night and follow with moisturizer.
- Daily UV Protection: Apply broad-spectrum sunscreen (SPF 30 or higher) every morning to protect dermal collagen from UV breakdown.
- Hyaluronic Acid Serums: Topical HA attracts surface moisture to temporarily plump fine lines, though it cannot fill deep structural grooves.
- Habit Adjustments: Cessation of smoking and sleeping on your back reduce mechanical pressure against facial skin.
Topical care cannot lift descending cheek fat pads or replace lost bone volume.
Clinical Smile Lines Treatments and Costs
When home care reaches its limits, an anti-aging skin treatment or clinical procedure offers targeted correction:
| Treatment Method | Onset of Results | Duration | Price Range in HCMC (2026) |
| Hyaluronic Acid Filler | Immediate | 6 to 18 Months | $77 – $537 (2 – 14M VND/cc) |
| Collagen Biostimulator | 2 to 4 Weeks | Up to 2 Years | $383 – $959 (10 – 25M VND/vial) |
| Thread Lift | Immediate | 1 to 2 Years | $575 – $1,074 (15 – 28M VND) |
| HIFU / Energy Lifting | Progressive (1-3 mos) | 1 to 2 Years | $383 – $613 (10 – 16M VND) |
| Facelift Surgery | 2 to 4 Weeks | 8 to 15 Years | $1,342 – $3,067 (35 – 80M VND) |

Injectable Treatment for Smile Lines
Injectable treatments offer immediate to progressive volume restoration for static folds:
1. Hyaluronic Acid Fillers
HA fillers inject soft gel beneath the fold to lift the depression level with surrounding skin. Results appear immediately and last 6 to 18 months depending on gel density and muscle movement around the mouth.
2. Collagen Biostimulators
Biostimulators introduce micro-particles (PLLA or CaHA) that prompt your skin to build its own collagen matrix over 2 to 4 weeks. This approach softens deep folds gradually, producing natural results lasting up to 2 years.
Safety Note: Injections near the nasolabial fold require an experienced physician with clear knowledge of facial vascular anatomy to avoid intra-arterial occlusion.
Thread Lifts and Facelift Surgery
When smile lines are caused by heavy cheek fat pads sagging over the fold, injecting filler alone can create a puffy look. Mechanical lifting repositions the tissue instead:
1. Thread Lift
PDO or PLLA cogged threads are inserted beneath the skin to catch and suspend sagging midface fat pads upward toward the temples. This lifts the overhang off the smile line crease without adding artificial volume.
[Aesthetic treatments for smile lines and sagging skin]
2. Surgical Facelift
For severe skin redundancy and heavy jowls, surgical tightening of the underlying SMAS layer provides definitive structural elevation and removes excess skin permanently.
Selecting the Right Approach for Your Needs
1. By Smile Line Type
- Nasolabial Folds (Nostril to Mouth Corner): Shallow grooves respond best to hyaluronic acid fillers or biostimulators (Sculptra/Radiesse) to replace lost volume. If the fold is caused by heavy, sagging cheek fat pads, thread lifts or a SMAS facelift are required to suspend the tissue upward rather than over-filling the crease.
- Marionette Lines (Mouth Corner to Chin): Downturned mouth corners caused by tissue descent and bone loss require structural support. Mild lines improve with targeted HA filler or biostimulator injections at the oral commissure. Severe sagging with jowling requires mechanical elevation via cogged thread lifts or surgical facial lifting.
- Perioral Vertical Lines (Lip Smoker Lines): Fine vertical creases along the lip borders stem from skin thinning and repetitive muscle movement. Micro-droplet HA mesotherapy, polynucleotide (salmon DNA) injections, or resurfacing lasers rebuild thin skin density.
2. By Age and Severity
- Under Age 35 with Mild Lines: Focus on prescription topical retinoids, daily broad-spectrum SPF 30+, and hydrating HA mesotherapy or skin boosters.
- Ages 35 to 50 with Static Grooves: Dermal fillers or collagen biostimulators effectively fill depressions when skin elasticity remains good.
- Ages 45+ with Heavy Skin Overhang: Combine thread lifts or surgical lifting with light filler touch-ups to address both structural tissue descent and localized volume loss.
Read Next
- Explore complete smile lines treatment prices in Vietnam
- Compare non-surgical options in our guide to thread face lift prices
- Review surgical options in our facelift cost in Vietnam guide
- Learn about non-invasive anti-aging skin treatments
Tailored Smile Line Solutions at Keangnam Korea
Wanting to refresh your lower face without looking “overdone”? Keangnam Korea Beauty Center is proud to be one of the select few elite medical centers in Vietnam officially licensed to treat international clients. Backed by multiple national awards for excellence in facial rejuvenation, we make high-end aesthetic care simple, safe, and stress-free.
Your ideal smile line treatment is just a message away. Call us at 0911 833 555 right now to get your free Face AI 3D scan, a complete price breakdown!
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